These will include:
- 'Front line' nursing and clinical care staff in secondary care settings involved in infection control and the treatment of burn patients.
- Clinical microbiologists based in secondary care settings with responsibility for infection diagnosis.
- Infection control teams responsible for monitoring and preventing hospital acquired infections.
- Academics and other scientists seeking to understand the pathogenesis of wound infections, and undertaking translational research.
There is also significant potential to adapt and exploit the novel technology as a platform technology for critical colonisation detection (infection) in other acute and chronic wounds.
2018 - 2019: GMP Manufacture and upscaling
2020 - 2021: Regulatory and ethical compliance, first human trial
Infected with Staphylococcus aureus or Pseudomonas aeruginosa.
The project team aims to create a wound dressing that provides an early indication of infection (illustrated in the figures below) at point of care (PoC). This would significantly enhance clinical decision-making - with the capability to rapidly distinguish the bacterial Clinical Colonisation Threshold (TREAT) from sub-clinical colonisation (DON'T TREAT).
Dressing response to Staphylococcus aureus toxins